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The 3‐Hydroxypiperidine Skeleton: Key Element in Natural Product Synthesis
Author(s) -
Wijdeven Marloes A.,
Willemsen Jorgen,
Rutjes Floris P. J. T.
Publication year - 2010
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200901494
Subject(s) - natural product , chemistry , moiety , scaffold , skeleton (computer programming) , combinatorial chemistry , natural (archaeology) , key (lock) , organic chemistry , computer science , programming language , ecology , biology , paleontology
The 3‐hydroxypiperidine moiety is a privileged scaffold that is encountered in many bioactive compounds and natural products. This review summarizes the investigations ofvarious research groups concerning the synthesis of natural products containing this scaffold.