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p ‐(Benzyloxy)calix[8]arene Synthesis Revisited: p ‐(Benzyloxy)calix[4]‐, p ‐(Benzyloxy)calix[5]‐, p ‐(Benzyloxy)calix[7]‐, and p ‐(Benzyloxy)bis(homooxa)calix[4]arenes
Author(s) -
Huc Vincent,
Npetgat Eloïne,
Guérineau Vincent,
Bourcier Sophie,
Dos Santos Amandine,
Guillot Régis,
Baltaze JeanPierre,
Martini Cyril
Publication year - 2010
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200901405
Subject(s) - calixarene , chemistry , supramolecular chemistry , stereochemistry , phenol , combinatorial chemistry , organic chemistry , molecule
A detailed investigation of the 4‐(benzyloxy)phenol/formaldehyde reaction shows that along with the previously described p ‐(benzyloxy)calix[8]arene and p ‐(benzyloxy)calix[6]arene, others calixarenes are observed and easily recovered on a preparative scale. All these new calixarenes are opening interesting perspectives for the synthesis of new supramolecular hosts, easily functionalized at the para position under very mild conditions and/or exhibiting a deep hydrophobic pocket.