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Design of Bisphosphonate‐Terminated Dendrimers
Author(s) -
Cavero Emma,
Zablocka Maria,
Caminade AnneMarie,
Majoral Jean Pierre
Publication year - 2010
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200901291
Subject(s) - dendrimer , chemistry , phosphorus , monomer , combinatorial chemistry , bisphosphonate , nanotechnology , bearing (navigation) , black phosphorus , organic chemistry , polymer , materials science , computer science , medicine , osteoporosis , endocrinology , optoelectronics , artificial intelligence
Abstract Several new methods for the synthesis of phosphorus dendrimers capped with biologically active azabisphosphonates are reported. Monomers bearing either azido or acetylenic groups were designed as building blocks either for attachment onto the surfaces of classical phosphorus dendrimers or for use in the construction of original dendrimers without the need for use of sensitive dichloro(monomethylhydrazino)thiophosphane.