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Baylis–Hillman Reaction of 1‐Formyl‐β‐carboline: One‐Step Synthesis of the Canthin‐6‐one Framework by an Unprecedented Cascade Cyclization Reaction
Author(s) -
Singh Virender,
Hutait Samiran,
Batra Sanjay
Publication year - 2009
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200900962
Subject(s) - chemistry , cascade , cascade reaction , baylis–hillman reaction , stereochemistry , medicinal chemistry , combinatorial chemistry , organic chemistry , adduct , catalysis , chromatography
Abstract A one‐step access to the canthin‐6‐one architecture by the Baylis–Hillman reaction of methyl 1‐formyl‐9 H ‐β‐carboline‐3‐carboxylate or 1‐formyl‐9 H ‐β‐carboline involving an unprecedented cascade cyclization reaction is reported. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)