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O ‐TMS‐α,α‐diphenyl‐( S )‐prolinol Modified with an Ionic Liquid Moiety: A Recoverable Organocatalyst for the Asymmetric Michael Reaction between α,β‐Enals and Dialkyl Malonates
Author(s) -
Maltsev Oleg V.,
Kucherenko Alexandr S.,
Zlotin Sergei G.
Publication year - 2009
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200900807
Subject(s) - chemistry , moiety , ionic liquid , catalysis , organocatalysis , derivative (finance) , michael reaction , organic chemistry , medicinal chemistry , enantioselective synthesis , financial economics , economics
O ‐TMS‐α,α‐diphenyl‐( S )‐prolinol derivative bearing an ionic liquid fragment was synthesized for the first time and proven to be an efficient catalyst for the asymmetric Michael reaction of aromatic α,β‐unsaturated aldehydes with dialkyl malonates. The prepared catalyst can be recovered four times and used in the same reaction without a decrease in activity or a decrease in the enantioselectivity of the reaction.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)