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Synthesis of Original 2‐Substituted 4‐Arylquinazolines by Microwave‐Irradiated Suzuki–Miyaura Cross‐Coupling Reactions
Author(s) -
Kabri Youssef,
Gellis Armand,
Vanelle Patrice
Publication year - 2009
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200900421
Subject(s) - chemistry , microwave irradiation , suzuki reaction , boronic acid , coupling reaction , coupling (piping) , combinatorial chemistry , microwave , organic chemistry , palladium , catalysis , mechanical engineering , physics , quantum mechanics , engineering
Original 2‐substituted 4‐arylquinazolines have been synthesized by using a microwave‐assisted Suzuki–Miyaura cross‐coupling approach. The optimization and generalization of the Suzuki–Miyaura cross‐coupling reaction between 2‐substituted 4‐chloroquinazolines and various boronic acids are described herein. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
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