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Phosphane‐Free Palladium‐Catalyzed Carbonylative Suzuki Coupling Reaction of Aryl and Heteroaryl Iodides
Author(s) -
Tambade Pawan J.,
Patil Yogesh P.,
Panda Anil G.,
Bhanage Bhalchandra M.
Publication year - 2009
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200900219
Subject(s) - chemistry , aryl , iodide , catalysis , palladium , carbonylation , coupling reaction , organic chemistry , medicinal chemistry , reaction conditions , combinatorial chemistry , carbon monoxide , alkyl
The carbonylative cross‐coupling reaction of an arylboronic acid with an aryl iodide and a heteroaryl iodide to give unsymmetrical biaryl ketones was carried out by using Pd(tmhd) 2 /Pd(OAc) 2 as a phosphane‐free catalyst. Various aryl and heteroaryl iodides with different arylboronic acid derivatives provided good to excellent yields of the desired products under optimized reaction conditions.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
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