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Synthesis of Chiral Amines Using α‐Amino Aldehydes (Eur. J. Org. Chem. 31/2008)
Author(s) -
Hili Ryan,
Baktharaman Sivaraj,
Yudin Andrei K.
Publication year - 2008
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200890084
Subject(s) - aldehyde , chemistry , cover (algebra) , organic chemistry , engineering , catalysis , mechanical engineering
The cover picture is an attempt to represent a cornucopia of molecules that are derived from α‐amino aldehydes. One hundred years ago, Emil Fischer attempted to prepare glycinal, a prototypical α‐amino aldehyde. Although glycinal resisted isolation and was found to be too unstable, it did provide a foundation for numerous synthetic studies of related molecules. Over the last century this field has flourished, proving the lasting value of these important synthetic intermediates. A. K.Yudin et al. summarize the latest trends in α‐amino aldehyde synthesis and applications on p. 5201 ff. The cover art was created by Mr. Ryan Hili. The authors gratefully acknowledge ongoing financial support from NSERC.