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Copper‐Catalyzed Asymmetric Allylic Alkylation (Eur. J. Org. Chem. 22/2008)
Author(s) -
Falciola Caroline A.,
Alexakis Alexandre
Publication year - 2008
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200890057
Subject(s) - chemistry , tsuji–trost reaction , enantioselective synthesis , allylic rearrangement , stereoselectivity , alkylation , catalysis , copper , ring (chemistry) , combinatorial chemistry , medicinal chemistry , stereochemistry , organic chemistry
The cover picture shows a figurative illustration of the copper‐catalytic cycle for the asymmetric allylic alkylation and its powerful stereoselective control over the regio‐, chemo‐ and enantioselective allylic ring opening of oxiranes or S N 2′ displacement of leaving groups. This Microreview by C. A. Falciola and A. Alexakis on p. 3765 ff. covers the field from the early stages of diastereoselective procedures to the more recent highly efficient catalytic protocols.