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Carbonylative Suzuki–Miyaura Coupling of Arylboronic Acids with Aryl Iodides Catalyzed by the MCM‐41‐Supported Bidentate Phosphane Palladium(II) Complex
Author(s) -
Cai Mingzhong,
Zheng Guomin,
Zha Lingfang,
Peng Jian
Publication year - 2009
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200801253
Subject(s) - chemistry , palladium , anisole , aryl , denticity , catalysis , carbon monoxide , selectivity , organic chemistry , medicinal chemistry , carbonylation , polymer chemistry , crystal structure , alkyl
The first heterogeneous carbonylative Suzuki–Miyaura cross‐coupling reaction of arylboronic acids with aryl iodides under an atmospheric pressure of carbon monoxide has been achieved in anisole at 80 °C in the presence of a catalytic amount of an MCM‐41‐supported bidentate phosphane palladium(II) complex (MCM‐41‐2P‐Pd II ), yielding unsymmetrical biaryl ketones in good‐to‐high yields. This polymeric palladium catalyst exhibited higher activity and selectivity than [PdCl 2 (PPh 3 ) 2 ] and can be reused at least 10 times without any decrease in activity. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)