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Cap‐Assisted Synthesis of Hetero‐Trifunctional Cyclodextrins, from Flamingo Cap to Bascule Bridge
Author(s) -
Sollogoub Matthieu
Publication year - 2009
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200800930
Subject(s) - regioselectivity , chemistry , cyclodextrin , bridge (graph theory) , combinatorial chemistry , stereochemistry , organic chemistry , catalysis , medicine
This microreview focuses on the use of cyclodextrin‐capping for the selective synthesis of cyclodextrins bearing three different functionalities. Three strategies have been employed and are discussed: dissymmetrical capping, regioselective opening of a symmetrical cap, and the more efficient cap‐oriented regioselective deprotection. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)