Synthesis of Oligosaccharides Related to a Biodynamic Saponin from  Calamus Insignis  as Their Propargyl Glycosides | Zendy

Dasgupta Somnath | Zendy; Mukhopadhyay Balaram | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Synthesis of Oligosaccharides Related to a Biodynamic Saponin from Calamus Insignis as Their Propargyl Glycosides

Author(s) -

Dasgupta Somnath,

Mukhopadhyay Balaram

Publication year - 2008

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.200800834

Subject(s) - chemistry , glycoside , calamus , saponin , rhamnose , glycosylation , propargyl , carbohydrate , total synthesis , protecting group , glucuronic acid , organic chemistry , stereochemistry , polysaccharide , botany , biochemistry , catalysis , medicine , alternative medicine , alkyl , pathology , biology

The total synthesis of the carbohydrate portion (penta‐and tetrasaccharides) of steroidal saponins, isolated from Calamus insignis , is reported. A simple route is followed, starting from commercially available D ‐glucose and L ‐rhamnose, through high‐yielding protecting group manipulation strategies. Sulfuric acid immobilized on silica (H 2 SO 4 /silica) was used as an effective Brönsted acid source in conjunction with N ‐iodosuccinimide for activation of thioglycosides or alone for trichloroacetimidate donors in key glycosylation steps. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research