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A Click Reaction for Fluorescent Labelling: Application of the 1,3‐Dipolar Cycloaddition Reaction
Author(s) -
Langhals Heinz,
Obermeier Andreas
Publication year - 2008
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200800805
Subject(s) - chemistry , cycloaddition , labelling , click chemistry , fluorescence , 1,3 dipolar cycloaddition , perylene , fluorescent labelling , combinatorial chemistry , photochemistry , organic chemistry , molecule , biochemistry , catalysis , physics , quantum mechanics
The copper‐catalysed 1,3‐dipolar cycloaddition of azides with terminal alkynes was use to introduce a highly fluorescent and photostable perylene‐tetracarboxdiimide label.Fluorescent labelling of human hormones and applications are discussed. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)