Synthesis of 1‐Amino‐1 H ‐indole‐3‐carboxylates by Copper(I)‐Catalyzed Intramolecular Amination of Aryl Bromides | Zendy

Melkonyan Ferdinand | Zendy; Topolyan Artyom | Zendy; Yurovskaya Marina | Zendy; Karchava Alexander | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Synthesis of 1‐Amino‐1 H ‐indole‐3‐carboxylates by Copper(I)‐Catalyzed Intramolecular Amination of Aryl Bromides

Author(s) -

Melkonyan Ferdinand,

Topolyan Artyom,

Yurovskaya Marina,

Karchava Alexander

Publication year - 2008

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.200800777

Subject(s) - chemistry , amination , intramolecular force , indole test , catalysis , copper , aryl , medicinal chemistry , combinatorial chemistry , organic chemistry , stereochemistry , alkyl

A simple route to various N ‐substituted 1‐amino‐1 H ‐indole‐3‐carboxylates by use of copper(I)‐catalyzed intramolecular N ‐arylation has been established. For the preparation of N ‐monosubstituted and N ‐unsubstituted derivatives, the cyclization of Boc‐protected enehydrazines and subsequent deprotection were applied. Furthermore, 1‐alkoxyindole‐3‐carboxylates can be synthesized by use of the same protocol(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research