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Fluorinated Johnson Reagent for Transfer‐Trifluoromethylation to Carbon Nucleophiles
Author(s) -
Noritake Shun,
Shibata Norio,
Nakamura Shuichi,
Toru Takeshi,
Shiro Motoo
Publication year - 2008
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200800419
Subject(s) - trifluoromethylation , chemistry , reagent , nucleophile , electrophile , tetrafluoroborate , trifluoromethyl , organic chemistry , combinatorial chemistry , ionic liquid , catalysis , alkyl
A novel reagent, [(oxido)phenyl(trifluoromethyl)‐λ 4 ‐sulfanylidene]dimethylammonium tetrafluoroborate has been developed for the electrophilic trifluoromethylation of carbon nucleophiles. The reagent was designed as a trifluorinated version of a Johnson‐type methyl‐transfer reagent. The firstexample of vinylogous trifluoromethylation of dicyanoalkylidenes is also demonstrated.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)