Premium
Copper Zeolites as Green Catalysts for Multicomponent Reactions of Aldehydes, Terminal Alkynes and Amines: An Efficient and Green Synthesis of Propargylamines
Author(s) -
Patil Meghshyam K.,
Keller Murielle,
Reddy Benjaram M.,
Pale Patrick,
Sommer Jean
Publication year - 2008
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200800359
Subject(s) - chemistry , catalysis , solvent , copper , organic chemistry , heterogeneous catalysis , aldehyde , terminal (telecommunication) , combinatorial chemistry , telecommunications , computer science
Cu I ‐modified zeolites, especially Cu I ‐USY, have proved to be very efficient catalysts in multicomponent reactions, allowing for a solvent‐free synthesis of propargylamines from aldehydes, amines, and terminal alkynes. With a heterogeneous catalyst and in the absence of solvent, this process is among the greenest ever reported. A mechanism has been proposed for this three‐component reaction.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom