Combination of RCM and the Pauson–Khand Reaction: One‐Step Synthesis of Tricyclic Structures | Zendy

Rosillo Marta | Zendy; Arnáiz Eduardo | Zendy; Abdi Delbrin | Zendy; BlancoUrgoiti Jaime | Zendy; Domínguez Gema | Zendy; PérezCastells Javier | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Combination of RCM and the Pauson–Khand Reaction: One‐Step Synthesis of Tricyclic Structures

Author(s) -

Rosillo Marta,

Arnáiz Eduardo,

Abdi Delbrin,

BlancoUrgoiti Jaime,

Domínguez Gema,

PérezCastells Javier

Publication year - 2008

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.200800332

Subject(s) - chemistry , enyne metathesis , intramolecular force , tricyclic , pauson–khand reaction , heteroatom , alkyne , ring closing metathesis , enyne , metathesis , combinatorial chemistry , stereochemistry , salt metathesis reaction , ring (chemistry) , organic chemistry , catalysis , polymerization , polymer

The combination of ring‐closing metathesis (RCM) followed by an intramolecular Pauson–Khand reaction gives direct entry to tricyclic compounds. The RCM was carried out on a hexacarbonylcobalt‐complexed alkyne, this complex acting as a protecting group against enyne metathesis. The procedure was studied for dienynes containing heteroatoms and allows the building of [6,5,5] and [7,5,5] tricyclic systems. The feasibility of the process depends strongly on the nature of the substrate.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research