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An Efficient Method for the Synthesis of Benzo[ f ]quinoline and Benzo[ a ]phenanthridine Derivatives Catalyzed by Iodine by a Three‐Component Reaction of Arenecarbaldehyde, Naphthalen‐2‐amine, and Cyclic Ketone
Author(s) -
Wang XiangShan,
Li Qing,
Yao ChangSheng,
Tu ShuJiang
Publication year - 2008
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200800287
Subject(s) - phenanthridine , chemistry , quinoline , iodine , catalysis , amine gas treating , ketone , medicinal chemistry , organic chemistry
A mild, efficient, and general method for the synthesis of benzo[ f ]quinoline and benzo[ a ]phenanthridine derivatives by a three‐component reaction of arenecarbaldehyde, naphthalen‐2‐amine, and cyclic ketone using iodine as catalyst is described. A possible reaction mechanism for the formation of the product is proposed based on further experimental results.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)