Synthesis of Natural Product Derivatives Containing 2,4‐Concatenated Oxazoles | Zendy

Hernández Delia | Zendy; Riego Estela | Zendy; Albericio Fernando | Zendy; Álvarez Mercedes | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Synthesis of Natural Product Derivatives Containing 2,4‐Concatenated Oxazoles

Author(s) -

Hernández Delia,

Riego Estela,

Albericio Fernando,

Álvarez Mercedes

Publication year - 2008

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.200800111

Subject(s) - oxazole , chemistry , ring (chemistry) , natural product , amide , combinatorial chemistry , peptide bond , stereochemistry , peptide , organic chemistry , biochemistry

Herein is described the synthesis of several oxazole‐containing derivatives of IB‐01211. The macrocyclization reaction of peptide 14 containing a concatenated triazole was successful and afforded 3 by amide bond formation. However, for those compounds containing quaterazoles or quinqueazoles, the oxazole ring had to be formed during macrocyclization. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research