Combined Metalation–Cross Coupling Strategies: A Synthesis of Schumanniophytine by a Key Biaryl  O ‐Carbamate Remote Anionic Fries Rearrangement | Zendy

Macklin Todd K. | Zendy; Reed Mark A. | Zendy; Snieckus Victor | Zendy

Premium

Combined Metalation–Cross Coupling Strategies: A Synthesis of Schumanniophytine by a Key Biaryl O ‐Carbamate Remote Anionic Fries Rearrangement

Author(s) -

Macklin Todd K.,

Reed Mark A.,

Snieckus Victor

Publication year - 2008

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.200701116

Subject(s) - chemistry , metalation , fries rearrangement , carbamate , combinatorial chemistry , stereochemistry , medicinal chemistry , organic chemistry , catalysis

A short synthesis of the alkaloid schumanniophytine ( 1 ) starting from simple building blocks and involving directed ortho metalation (D o M), Suzuki–Miyaura cross coupling, and a key ortho ‐silicon‐induced O ‐carbamate remote anionic Fries rearrangement ( 3 ) is described. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research