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Synthesis of a Tripodal Scaffold for Solid Phase Synthesis of Artificial Receptors
Author(s) -
Van der Plas Steven E.,
Gea An,
Figaroli Sara,
De Clercq Pierre J.,
Madder Annemieke
Publication year - 2008
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200701104
Subject(s) - chemistry , scaffold , solid phase synthesis , combinatorial chemistry , convergent synthesis , combinatorial synthesis , nanotechnology , biochemistry , biomedical engineering , medicine , peptide , materials science
A convergent synthesis for the preparation of a new orthogonally protected tripodal scaffold has been developed. The scaffold was successfully coupled to a Tentagel solid support and further derivatised at the three attachment points demonstrating its possible use for combinatorial chemistry. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)