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Continuous Flow Reactors, a Tool for the Modern Synthetic Chemist
Author(s) -
Wiles Charlotte,
Watts Paul
Publication year - 2008
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200701041
Subject(s) - chemistry , chemist , continuous flow , transferability , nanotechnology , biochemical engineering , flow chemistry , scalability , combinatorial chemistry , computer science , organic chemistry , engineering , database , materials science , logit , machine learning
The competitive nature of the chemical industry means that researchers involved in product development and lead compound generation are under continued pressure to identify, and develop, promising programmes of research in order to secure vital intellectual property. The potential of a compound, however, depends not only on structural complexity, but also on the ability to prepare the compound via a scalable synthetic pathway. Consequently, micro reaction and continuous flow technologies have captured the attention of the modern synthetic chemist as they enable reactions to beperformed with an unprecedented level of control, affording excellent transferability between laboratory based investigations and subsequent production scales. With these features in mind, this Microreview focuses on recent developments made in the field of micro reaction technology, highlighting the advantages associated with its use through the synthesis of a diverse array of molecules.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)