Synthesis of Novel Angular Heterocyclic Lignans by an InCl 3 ‐Catalyzed Friedel–Crafts‐Type Cyclization | Zendy

Dorbec Matthieu | Zendy; Florent JeanClaude | Zendy; Monneret Claude | Zendy; Rager MarieNoëlle | Zendy; Fosse Céline | Zendy; Bertounesque Emmanuel | Zendy

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Synthesis of Novel Angular Heterocyclic Lignans by an InCl 3 ‐Catalyzed Friedel–Crafts‐Type Cyclization

Author(s) -

Dorbec Matthieu,

Florent JeanClaude,

Monneret Claude,

Rager MarieNoëlle,

Fosse Céline,

Bertounesque Emmanuel

Publication year - 2008

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.200701027

Subject(s) - friedel–crafts reaction , chemistry , catalysis , organic chemistry , stereochemistry

The synthesis of a 1‐aryltetralin privileged structure‐based library of novel angular heterocyclic lignans is described. Indolotetralins 3 , tetrahydroquinolinotetralins 4 , and thiochromanotetralins 5 were obtained from the methyl ester of thuriferic acid 2 according to a three‐step procedure involving an InCl 3 ‐catalyzed Friedel–Crafts‐type cyclization as the key step.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)

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