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Modern Amination Reactions
Author(s) -
Kienle Marcel,
Reddy Dubbaka Srinivas,
Brade Katja,
Knochel Paul
Publication year - 2007
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200700391
Subject(s) - chemistry , amination , chloranil , reagent , organic chemistry , lithium (medication) , primary (astronomy) , electrophilic amination , palladium , nickel , oxidative coupling of methane , combinatorial chemistry , catalysis , polymer chemistry , medicine , physics , astronomy , endocrinology
The synthesis of functionalized aromatic and heteroaromatic amines has attracted much interest due to their importance as building blocks for pharmaceuticals, polymers, or materials. In this microreview, new developments involving palladium‐, nickel‐, and copper‐catalyzed amination reactions are discussed. The synthesis of functionalized secondary amines or diarylamines by addition of polyfunctionalized arylmagnesium reagents to nitroarenes or arylazo tosylates is also presented. Finally, primary, secondary, and tertiary amines prepared by the oxidative coupling of polyfunctional lithium amidocuprates using chloranil as oxidant are highlighted. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)