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A Convenient Route to 2‐Hydroxy‐ and 2,15‐Dihydroxyhexahelicene
Author(s) -
Teplý Filip,
Stará Irena G.,
Starý Ivo,
Kollárovič Adrian,
Luštinec Daniel,
Krausová Zuzana,
Šaman David,
Fiedler Pavel
Publication year - 2007
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200700381
Subject(s) - chemistry , naphthalene , intramolecular force , benzene , benzene derivatives , organic chemistry , combinatorial chemistry , medicinal chemistry , chemical synthesis , biochemistry , in vitro
2‐Hydroxy‐ and 2,15‐dihydroxyhexahelicene were synthesised from simple benzene and naphthalene building blocks by intramolecular Co I ‐ or Ni 0 ‐catalysed [2+2+2] cycloisomerisation of CH 3 O‐substituted aromatic triynes. This approach avoids vexing photodehydrocyclisation of stilbene‐type precursors, providing thus a useful alternative to classical procedures. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)