A Convenient and General Method for the Synthesis of Indole‐2,3‐dicarboxylates and 2‐Arylindole‐3‐carboxylates | Zendy

Sayyed Iliyas Ali | Zendy; Alex Karolin | Zendy; Tillack Annegret | Zendy; Schwarz Nicolle | Zendy; Michalik Dirk | Zendy; Beller Matthias | Zendy

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A Convenient and General Method for the Synthesis of Indole‐2,3‐dicarboxylates and 2‐Arylindole‐3‐carboxylates

Author(s) -

Sayyed Iliyas Ali,

Alex Karolin,

Tillack Annegret,

Schwarz Nicolle,

Michalik Dirk,

Beller Matthias

Publication year - 2007

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.200700310

Subject(s) - chemistry , hydroamination , domino , indole test , acetylene , alkyl , organic chemistry , combinatorial chemistry , catalysis

A transition‐metal‐free, simple and efficient one‐pot method for the synthesis of indole‐2,3‐dicarboxylates and 2‐arylindole‐3‐carboxylates is described. The corresponding products are obtained by a domino hydroamination/Fischerindole cyclization in good‐to‐excellent yields from easily available 1‐alkyl‐1‐phenylhydrazines and acetylene carboxylates.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)

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