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Squarrosidine and Pinillidine: 3,3′‐Fused Bis(styrylpyrones) from Pholiota squarrosa and Phellinus pini
Author(s) -
Kemami Wangun Hilaire V.,
Hertweck Christian
Publication year - 2007
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200700090
Subject(s) - chemistry , mushroom , stereochemistry , mycelium , botany , biology , food science
Two novel fungal phenylpropanoid‐derived polyketides, squarrosidine ( 8 ) and pinillidine ( 9 ), with potent xanthine oxidase (XO) inhibitory activities were isolated from the fruiting bodies of the mushroom Pholiota squarrosa and from the mycelium of Phellinus pini by bioassay‐guided isolation. Structural analyses revealed that both metabolites from the tree fungi represent unprecedented 3,3′‐fused bis(styrylpyrones). (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)