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Domino [2+2]/[2+1] and [3+2]/[2+1] Reaction Sequences of Alkynyl(alkoxy) Chromium Fischer Carbene Complexes
Author(s) -
PérezAnes Alexandra,
GarcíaGarcía Patricia,
SuárezSobrino Ángel Luis,
Aguilar Enrique
Publication year - 2007
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200700077
Subject(s) - carbene , chemistry , cyclopropanation , alkoxy group , chromium , adduct , domino , medicinal chemistry , cycloaddition , cascade reaction , acrylate , stereochemistry , organic chemistry , polymer , catalysis , monomer , alkyl
A tandem [2+2]/[2+1] sequence takes place between alkynyl(alkoxy) Fischer carbene complexes and 2,3‐dihydrofuran, producing three‐component adducts diastereoselectively in moderate yields. On the other hand, a [3+2]/[2+1] (1,3‐dipolar cycloaddition/cyclopropanation) sequence takes place between an alkynyl(alkoxy) Fischer carbene complex, trimethylsilyldiazomethane, and methyl acrylate or 2,3‐dihydrofuran. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)