Heptakis[2,3‐di‐ O ‐methyl‐6‐ O ‐( L ‐valine‐ tert ‐butylamide‐ N   α  ‐ylcarbonylmethyl)]‐β‐cyclodextrin: a New Multifunctional Cyclodextrin CSA for the NMR Enantiodiscrimination of Polar and Apolar Substrates | Zendy

UccelloBarretta Gloria | Zendy; Nazzi Samuele | Zendy; Balzano Federica | Zendy; Levkin Pavel A. | Zendy; Schurig Volker | Zendy; Salvadori Piero | Zendy

Premium

Heptakis[2,3‐di‐ O ‐methyl‐6‐ O ‐( L ‐valine‐ tert ‐butylamide‐ N α ‐ylcarbonylmethyl)]‐β‐cyclodextrin: a New Multifunctional Cyclodextrin CSA for the NMR Enantiodiscrimination of Polar and Apolar Substrates

Author(s) -

UccelloBarretta Gloria,

Nazzi Samuele,

Balzano Federica,

Levkin Pavel A.,

Schurig Volker,

Salvadori Piero

Publication year - 2007

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.200700018

Subject(s) - chemistry , valine , cyclodextrin , stereochemistry , nuclear magnetic resonance spectroscopy , enantiomer , medicinal chemistry , amino acid , organic chemistry , biochemistry

Heptakis[2,3‐di‐ O ‐methyl‐6‐ O ‐( L ‐valine‐ tert ‐butylamide‐ N α ‐ylcarbonylmethyl)]‐β‐cyclodextrin with methyl groups on the secondary sites and a diamide chiral selector on the primary ones showed considerable utility as a CSA in the NMR enantiodiscrimination of a wide spectrum of amino acid derivatives, while also allowing trisubstituted allenes to be enantiodiscriminated. Enantiodiscrimination processes were investigated by Diffusion‐Ordered SpectroscopY (DOSY). (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research