Premium
Cover Picture: An Expedient Route to New Spiroheterocycles: Synthesis and Structural Studies (Eur. J. Org. Chem. 21/2006)
Author(s) -
Goubert Marlène,
Canet Isabelle,
Sinibaldi MarieEve
Publication year - 2006
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200690042
Subject(s) - chemistry , cover (algebra) , substitution (logic) , stereochemistry , mechanical engineering , engineering , computer science , programming language
The cover picture shows an original and efficient approach to chiral 1,4,7,10‐tetraoxa‐ and 1,7‐dioxa‐4,10‐dithiaspiro[5.5]undecanes, involving a double substitution of a thiolate or an alcoholate on 1,3‐dichloropropanone O ‐benzyloxime followed by a “one‐pot” deprotection−spirocyclization process. The structure and configurations of all the synthesized spiroheterocycles were unambiguously established on the basis of NMR experiments. Details are discussed in the article by M. Goubert, I. Canet and M.‐E. Sinibaldi on p. 4805 ff.