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Cover Picture: Ruthenium‐Catalyzed Propargylation of Aromatic Compounds with Propargylic Alcohols (Eur. J. Org. Chem. 4/2006)
Author(s) -
Inada Youichi,
Yoshikawa Masato,
Milton Marilyn Daisy,
Nishibayashi Yoshiaki,
Uemura Sakae
Publication year - 2006
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200690008
Subject(s) - chemistry , ruthenium , propargyl , intramolecular force , electrophilic aromatic substitution , catalysis , intermolecular force , electrophile , selectivity , medicinal chemistry , aromaticity , organic chemistry , combinatorial chemistry , molecule
The cover picture shows that thiolate‐bridged diruthenium complexes promote intermolecular and intramolecular propargylation of aromatic compounds with propargylic alcohols to give the corresponding propargylated aromatic compounds in high yields with complete selectivity. The reaction is considered to be an electrophilic substitution of the aromatic compounds by the ruthenium‐stabilized propargyl cation. Details are described in the article by Y. Nishibayashi et al. on p. 881 ff.