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Aziridinyl Vinyl Ketones from the Asymmetric Catalytic Aziridination Reaction
Author(s) -
Deng Yonghong,
Lee Young Rok,
Newman Cory A.,
Wulff William D.
Publication year - 2007
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200601126
Subject(s) - synthon , chemistry , catalysis , lewis acids and bases , organic chemistry , ligand (biochemistry) , boron , asymmetric induction , enantioselective synthesis , nitroaldol reaction , carbon fibers , lewis acid catalysis , medicinal chemistry , polymer chemistry , biochemistry , materials science , receptor , composite number , composite material
Under the aegis of boron Lewis acids, prepared from either the vanol or vapol ligand, vinyl aziridinyl ketones can be obtained with a high degree of asymmetric induction from the catalytic asymmetric aziridination reaction (AZ) of imines and vinyl diazomethyl ketones. The products have potential as synthons for five‐carbon chiral amines. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)