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Repetitive Application of a Fluorous Chiral BINAP–Ru Complex in the Asymmetric Hydrogenation of Olefins
Author(s) -
Horn Joachim,
Bannwarth Willi
Publication year - 2007
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200601068
Subject(s) - chemistry , binap , leaching (pedology) , asymmetric hydrogenation , ruthenium , catalysis , enantioselective synthesis , organic chemistry , noyori asymmetric hydrogenation , reuse , ligand (biochemistry) , medicinal chemistry , combinatorial chemistry , waste management , biochemistry , environmental science , receptor , soil science , engineering , soil water
A trisperfluoroalkylsilyl‐modified ( S )‐BINAP ligand has been prepared and its pertinent Ru complex applied to the asymmetric hydrogenation of olefins. Efficient separation of the Ru catalyst by filtration and its reuse was achieved. Relative to the untagged complex with a Ru‐leaching of 300 ppm, leaching into the product was low (1.6–4.9 ppm). (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)