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Stereoselective Intramolecular Oxazine Formation by a π‐Allylpalladium Complex Catalyzed by Pd 0
Author(s) -
Joo JaeEun,
Lee KeeYoung,
Pham VanThoai,
Ham WonHun
Publication year - 2007
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200600927
Subject(s) - chemistry , palladium , intramolecular force , benzamide , catalysis , stereoselectivity , oxazines , medicinal chemistry , stereochemistry , organic chemistry
An efficient procedure for synthesizing oxazines was developed by the palladium(0)‐catalyzed intramolecular cyclization of a benzamide through a π‐allylpalladium(II) complex. Unlike other palladium‐catalyzed reactions, the temperature was found to be a key factor in determining the stereochemistry of the oxazine. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)