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Chiral 6,6′‐Bis(oxazolyl)‐1,1′‐biphenyls as Ligands for Copper(I)‐Catalyzed Asymmetric Cyclopropanation
Author(s) -
Khanbabaee Karamali,
Basceken Sinan,
Flörke Ulrich
Publication year - 2007
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200600806
Subject(s) - cyclopropanation , oxazoline , chemistry , biphenyl , copper , catalysis , enantioselective synthesis , combinatorial chemistry , organic chemistry , medicinal chemistry , stereochemistry
A series of chiral bis(oxazoline)s with biphenyl backbones were synthesized from enantiomerically pure ( S )‐ and ( R )‐hexabenzyloxydiphenic acid ( 1 ) and their utility in copper(I)‐catalyzed asymmetric cyclopropanation was investigated. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)