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A New Synthetic Route for the Preparation of 1,10‐Phenanthroline Derivatives
Author(s) -
Moudam Omar,
Ajamaa Fettah,
Ekouaga Allan,
Mamlouk Hind,
Hahn Uwe,
Holler Michel,
Welter Richard,
Nierengarten JeanFrançois
Publication year - 2007
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200600772
Subject(s) - phenanthroline , chemistry , reagent , combinatorial chemistry , reactivity (psychology) , bromide , benzyl bromide , organic chemistry , catalysis , medicine , alternative medicine , pathology
The intermediate resulting from the addition of an organolithium reagent to 1,10‐phenanthroline has been quenched with benzyl bromide. The resulting protected dihydrophenanthroline intermediate is thus stabilized and can be used for further chemical transformations. This strategy allows to modify the reactivity of the phenanthroline backbone and offers a unique opportunity to perform chemical modifications that would not be possible when starting from 1,10‐phenanthroline. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)