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Recent Advances in Asymmetric Organocatalytic 1,4‐Conjugate Additions
Author(s) -
Tsogoeva Svetlana B.
Publication year - 2007
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200600653
Subject(s) - chemistry , conjugate , nucleophile , domino , nitro , organocatalysis , addition reaction , organic chemistry , nitroaldol reaction , aldol reaction , carbon fibers , enantioselective synthesis , combinatorial chemistry , catalysis , alkyl , composite number , composite material , mathematical analysis , materials science , mathematics
Recent progress in the field of asymmetric organocatalytic 1,4‐conjugate addition reactions, regarded as belonging among the more synthetically important carbon–carbon bond‐forming reactions, is described. The focus is on some recent advances in the following selected reactions: additions of various nucleophiles to α,β‐unsaturated cyclic and acyclic enals, enones, vinyl sulfones and nitro olefins, addition of malonates and/or ketones to acyclic enones, or of aldehydes and ketones to vinyl ketones and nitro olefins, together with some multicomponent domino reactions. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)