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Constrained Carbenes
Author(s) -
Rosenberg Murray G.,
Brinker Udo H.
Publication year - 2006
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200600547
Subject(s) - chemistry , carbene , cyclopropane , supramolecular chemistry , reactive intermediate , divalent , cyclopropanation , catalysis , combinatorial chemistry , organic chemistry , computational chemistry , crystal structure , ring (chemistry)
Abstract Carbenes traditionally have been used for cyclopropane synthesis but little else, since their reactions are difficult to control. However, the burgeoning discipline of supramolecular carbene chemistry—reactions in which highly reactive, divalent carbon intermediates are generated within the confines of host compounds—is making steady progress towards solving this problem. Various carbenes generated within cyclodextrins, hemicarcerands, and zeolites demonstrate increased selectivities and lifetimes since their usual decay pathways are blocked. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)