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Regioselective 5‐, 4‐, and 2‐Substitution of ( S )‐6‐Chloronicotine and 4‐Substitution of ( S )‐5‐Chloronicotine
Author(s) -
Wagner Florence F.,
Comins Daniel L.
Publication year - 2006
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200600415
Subject(s) - regioselectivity , chemistry , substitution (logic) , yield (engineering) , substitution reaction , stereochemistry , medicinal chemistry , organic chemistry , catalysis , materials science , computer science , metallurgy , programming language
A variety of novel 2‐, 4‐, and 5‐substituted 6‐chloronicotine and 4‐substituted 5‐chloronicotine derivatives have been synthesized in a regioselective manner in moderate to high yield from ( S )‐6‐chloronicotine and ( S )‐5‐chloronicotine, respectively. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)