Prenylated Stilbenes and Their Novel Biogenetic Derivatives from  Artocarpus chama | Zendy

Wang YongHong | Zendy; Hou AiJun | Zendy; Chen DaoFeng | Zendy; Weiller Markus | Zendy; Wendel Albrecht | Zendy; Staples Richard J. | Zendy

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Prenylated Stilbenes and Their Novel Biogenetic Derivatives from Artocarpus chama

Author(s) -

Wang YongHong,

Hou AiJun,

Chen DaoFeng,

Weiller Markus,

Wendel Albrecht,

Staples Richard J.

Publication year - 2006

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.200600278

Subject(s) - chemistry , prenylation , stereochemistry , cytotoxicity , nuclear magnetic resonance spectroscopy , mass spectrometry , organic chemistry , biochemistry , chromatography , enzyme , in vitro

Two new prenylated stilbenes, artochamins F ( 1 ) and G ( 2 ), and their four novel derivatives, artochamins H–K ( 3 – 6 ), were isolated from the stems of Artocarpus chama . Their structures were elucidated mainly by NMR spectroscopy and mass spectrometry. The structure of 3 was confirmed by X‐ray crystallographic analysis. The origin of 3 – 6 could be assumed biogenetically from 2 . The cytotoxicity of these compounds against HepG2 cells was evaluated. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)

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