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Prenylated Stilbenes and Their Novel Biogenetic Derivatives from Artocarpus chama
Author(s) -
Wang YongHong,
Hou AiJun,
Chen DaoFeng,
Weiller Markus,
Wendel Albrecht,
Staples Richard J.
Publication year - 2006
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200600278
Subject(s) - chemistry , prenylation , stereochemistry , cytotoxicity , nuclear magnetic resonance spectroscopy , mass spectrometry , organic chemistry , biochemistry , chromatography , enzyme , in vitro
Two new prenylated stilbenes, artochamins F ( 1 ) and G ( 2 ), and their four novel derivatives, artochamins H–K ( 3 – 6 ), were isolated from the stems of Artocarpus chama . Their structures were elucidated mainly by NMR spectroscopy and mass spectrometry. The structure of 3 was confirmed by X‐ray crystallographic analysis. The origin of 3 – 6 could be assumed biogenetically from 2 . The cytotoxicity of these compounds against HepG2 cells was evaluated. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)