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Titanocene( II )‐Promoted Cross‐Coupling of Unsaturated Compounds
Author(s) -
Ogata Akitoshi,
Nemoto Masami,
Arai Koutarou,
Kobayashi Kenji,
Tsubouchi Akira,
Takeda Takeshi
Publication year - 2006
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200500976
Subject(s) - chemistry , allylic rearrangement , reagent , conjugated system , double bond , medicinal chemistry , triple bond , stereochemistry , organic chemistry , catalysis , polymer
Vinyl pivalate in the presence of the titanocene( II ) reagent Cp 2 Ti[P(OEt) 3 ] 2 reacts both with nonpolar C≡C triple bonds and with polar C=O double bonds, to produce conjugated dienes and allylic alcohols, respectively. Similar alkenylation also takes place when ( Z )‐alkenyl sulfones are treated with alkynes and carbonyl compounds. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)