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Synthesis of Pulvinic Acid and Norbadione A Analogues by Suzuki–Miyaura Cross‐Coupling of Benzylated Intermediates
Author(s) -
DesageEl Murr Marine,
Nowaczyk Stéphanie,
Le Gall Thierry,
Mioskowski Charles
Publication year - 2006
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200500837
Subject(s) - chemistry , coupling (piping) , sequence (biology) , combinatorial chemistry , organic chemistry , coupling reaction , stereochemistry , catalysis , biochemistry , materials science , metallurgy
Pulvinic acid and norbadione A analogues can be prepared by Suzuki–Miyaura cross‐coupling of functionalized arylboronic esters with appropriate vinyl triflates, in which the hydroxy functions are protected either with methyl or benzyl groups, the latter being cleaved in a more reliable fashion at the end of the synthetic sequence. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)