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A Concise Total Synthesis of Antifungal Antibiotic (+)‐Preussin
Author(s) -
Gogoi Naminita,
Boruwa Joshodeep,
Barua Nabin C.
Publication year - 2006
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200500833
Subject(s) - chemistry , stereocenter , natural product , antifungal , total synthesis , stereochemistry , enantioselective synthesis , catalysis , combinatorial chemistry , organic chemistry , microbiology and biotechnology , biology
A short synthesis of the pharmacologically important natural product (+)‐preussin is described. Two asymmetric C–C bond‐formation reactions mediated by binaphthol‐derived asymmetric catalysts have been applied to control the stereochemistry of its three stereocenters. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)
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