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Reduction of Multiple Bonds without Hydrogen or Hydride Complexes: Samarium Diiodide as a Mild Reducing Reagent
Author(s) -
Concellón José M.,
RodríguezSolla Humberto
Publication year - 2006
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200500771
Subject(s) - samarium diiodide , samarium , chemistry , reagent , reducing agent , combinatorial chemistry , hydride , organic chemistry , metal
The use of samarium diiodide as a mild and selective reducing agent has become an important tool in organic synthesis. Many reducing agents are reported in the literature. However, due to their low chemoselectivities and various other drawbacks, samarium diiodide has become a useful and readily available reagent. This manuscript provides an update on earlier reviews describing conventional reduction processes of multiple bonds promoted by samarium diiodide. The most recent developments in the use of samarium metal in this field are also discussed. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)