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Straightforward Synthesis of Non‐Natural Selenium Containing Amino Acid Derivatives and Peptides
Author(s) -
Braga Antonio L.,
Lüdtke Diogo S.,
Paixão Márcio W.,
Alberto Eduardo E.,
Stefani Hélio A.,
Juliano Luiz
Publication year - 2005
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200500530
Subject(s) - chemistry , selenium , amino acid , peptide , organic chemistry , peptide synthesis , combinatorial chemistry , stereochemistry , biochemistry
Abstract A series of non‐natural selenium‐containing amino acid derivatives and peptides have been synthesized, in a flexible and modular strategy. The peptide coupling reaction between N ‐protected amino acids and chiral β‐seleno amines afforded the desired products in high yields. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005)