Regioselective Synthesis of Silylated Pyrazolines and Indazolines by Reaction of Pyrazolium and Indazolium Salts with Silyllithium Reagents | Zendy

GonzálezNogal Ana M. | Zendy; Calle Mariola | Zendy; Calvo Luis A. | Zendy; Cuadrado Purificación | Zendy; GonzálezOrtega Alfonso | Zendy

Premium

Regioselective Synthesis of Silylated Pyrazolines and Indazolines by Reaction of Pyrazolium and Indazolium Salts with Silyllithium Reagents

Author(s) -

GonzálezNogal Ana M.,

Calle Mariola,

Calvo Luis A.,

Cuadrado Purificación,

GonzálezOrtega Alfonso

Publication year - 2005

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.200500438

Subject(s) - chemistry , synthon , regioselectivity , reagent , silylation , ring (chemistry) , organic chemistry , medicinal chemistry , catalysis

Pyrazolium salts react with dimethylphenylsilyl‐ and tert ‐butyldiphenylsilyllithium to give, in general, only one of the two possible 5‐silyl‐3‐pyrazolines. On the other hand, indazolium and isoindazolium salts lead to 3‐silylindazolines and occasionally to compounds resulting from the opening or expansion of the heterocyclic ring. All of these compounds are interesting synthons in organic chemistry. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005)

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research