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Syntheses of New Chiral Phosphane Ligands by Diastereoselective Conjugate Addition of Phosphides to Enantiomerically Pure Acceptor‐Substituted Olefins from the Chiral Pool
Author(s) -
Wiese Burkhard,
Knühl Guido,
Flubacher Dietmar,
Prieß Jan W.,
Ulriksen nee Laursen Bolette,
Brödner Kerstin,
Helmchen Günter
Publication year - 2005
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200500144
Subject(s) - stereocenter , chemistry , conjugate , enantioselective synthesis , acceptor , phosphorus , chirality (physics) , organic chemistry , addition reaction , catalysis , medicinal chemistry , chiral symmetry , mathematical analysis , physics , mathematics , condensed matter physics , quantum mechanics , quark , nambu–jona lasinio model
A variety of new chiral phosphanes were prepared by highly diastereoselective additions of phosphanes to α,β‐unsaturated carbonyl compounds and related acceptor‐substituted olefins derived from myrtenal as ex chiral pool source. Monophosphanes with astereogenic as well as stereogenic phosphorus are described. In addition diphosphanes were prepared by a highly diastereoselective double conjugate addition of a secondary diphosphane. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005)