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Fluoroalkylation of Porphyrins: A Facile Synthesis of Trifluoromethylated Porphyrins by a Palladium‐Catalyzed Cross‐Coupling Reaction
Author(s) -
Liu Chao,
Chen QingYun
Publication year - 2005
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200500027
Subject(s) - chemistry , palladium , catalysis , coupling reaction , alkynylation , combinatorial chemistry , reaction conditions , organic chemistry , medicinal chemistry
Various trifluoromethylated porphyrins can be conveniently synthesized in high yields by the reaction of brominated porphyrins with FSO 2 CF 2 COOMe/CuI in the presence of catalytic amounts of Pd 2 (dba) 3 · CHCl 3 /AsPh 3 . (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005)