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Cover Picture: Transition Metal‐Catalyzed Carbon−Carbon Bond Formation with Grignard Reagents − Novel Reactions with a Classic Reagent (Eur. J. Org. Chem. 10/2004)
Author(s) -
Shinokubo Hiroshi,
Oshima Koichiro
Publication year - 2004
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200490020
Subject(s) - chemistry , reagent , catalysis , transition metal , carbon–carbon bond , organic synthesis , manganese , grignard reaction , carbon fibers , cobalt , coupling reaction , combinatorial chemistry , grignard reagent , organic chemistry , materials science , composite number , composite material
The cover picture shows a concept that the combination of a Grignard reagent (RMgX) with various transition metal catalysts opens up an opportunity to explore new reactions for carbon−carbon bond formation. Grignard reagents are the most classical organometallics and useful compounds in organic synthesis. The addition of transition metal salts to this classic reagent gives novel reaction patterns such as carbometallation, rearrangement, electron transfer, cross‐coupling, and so forth. Manganese‐, chromium‐, iron‐, and cobalt‐catalyzed carbon−carbon bond formation reactions with Grignard reagents are discussed in the Microreview by H. Shinokubo and K. Oshima on p. 2081 ff.