Premium
Transition Metal Catalyzed Decarboxylative Additions of Enolates
Author(s) -
Tunge Jon A.,
Burger Erin C.
Publication year - 2005
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200400865
Subject(s) - chemistry , decarboxylation , allylic rearrangement , aldol reaction , transition metal , catalysis , organic chemistry , metal
Transition metal catalyzed decarboxylation of β‐keto acids and esters provides a convenient route for the regiospecific generation of enolates under neutral conditions. Enolates generated by decarboxylation have been utilized in aldol and Michael additions as well as allylic alkylations. The scope and mechanisms of these transformations are discussed. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005)